3,4-Difluoronitrobenzene exhibits a unique chemical structure characterized by a benzene ring substituted with two fluorine atoms at the 3 and 4 positions, along with a nitro group (-NO2) attached to the ring. This compound exhibits notable reactivity due to the electron-withdrawing nature of both the fluorine and nitro groups. The presence of these substituents generates an increase in electrophilicity, making the benzene ring more susceptible to nucleophilic attack. As a result, 3,4-difluoronitrobenzene serves as a valuable intermediate in the synthesis of various complex compounds, particularly those with pharmacological applications.
- Its physical properties include a melting point of around 50 degrees Celsius and a boiling point of approximately 190 degrees Celsius.
- Furthermore, it demonstrates limited solubility in water but is miscible in common organic solvents.
The synthesis of 3,4-difluoronitrobenzene typically comprises a multi-step process wherein includes the nitration of fluorobenzene followed by selective fluorination. This compound has been extensively investigated due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Synthesis and Properties of 3,4-Difluoronitrobenzene
3,4-Difluoronitrobenzene exhibits a significant role in the realm of organic synthesis due to its unique structural characteristics. The synthesis of this compound can be achieved through various routes, with a commonly employed method involving the nitration of 1,2-difluorobenzene. This reaction typically utilizes a mixture of nitric acid and sulfuric acid as the nitrating agent, producing the desired 3,4-difluoronitrobenzene product.
The resulting compound exhibits distinct physicochemical properties that influence its reactivity and applications. Notably, the electron-withdrawing nature of the nitro group in 3,4-difluoronitrobenzene modifies its electrophilicity, making it susceptible to nucleophilic attack. This property renders it a versatile building block for the synthesis of complex organic molecules.
- Additionally, the presence of fluorine atoms in the molecule contributes to its durability and miscibility in various solvents.
CAS No. for 3,4-Difluoronitrobenzene: Identifying This Compound
When working with chemicals, accurately pinpointing them is crucial for safety and accurate results. A key tool in this process is the CAS Registry Number, a unique identifier assigned to every chemical compound. For 3,4-Difluoronitrobenzene, this number is vital for ensuring you are working with the correct substance.
The CAS No. for 3,4-Difluoronitrobenzene is 105387-96-3. This unique identifier can be used to locate information about the compound in databases and research materials. Understanding its properties, hazards, and safe handling procedures is paramount when dealing with this chemical.
Applications of 3,4-Difluoronitrobenzene in Research
3,4-Difluoronitrobenzene finds a broad range of applications in research. Its unique configuration and physical properties make it to be utilized as a valuable intermediate in the synthesis of novel organic compounds. Researchers harness 3,4-difluoronitrobenzene for its versatility in synthesizing new materials with specific properties. Furthermore, website this compound acts as a valuable resource in the study of chemical phenomena. Its capabilities cover diverse research areas, including organic chemistry.
Safety Considerations for Handling 3,4-Difluoronitrobenzene
When handling 3,4-difluoronitrobenzene, it is essential to prioritize personal protection. This substance can be hazardous if not managed properly. Always perform operations in a well-ventilated area and utilize appropriate personal protective equipment (PPE), including gloves, safety glasses, and a protective smock.
Before handling with 3,4-difluoronitrobenzene, meticulously review the material safety data sheet (MSDS) provided by the provider. This resource will provide specific instructions on potential risks, first response, and containment procedures.
- Avoid exposure with mucous membranes. In the event of exposure, promptly flush the affected area with copious amounts of clean water for at least quarter hour.
- Preserve 3,4-difluoronitrobenzene in a well-ventilated place away from ignition points and hazardous compounds.
- Dispose of 3,4-difluoronitrobenzene properly in accordance with local regulations.
Spectral Characterization of 3,4-Difluoronitrobenzene
The spectral characterization of this fluorinated nitroarene is crucial for elucidating its chemical properties and potential applications.
IR|UV-Vis|NMR spectroscopy provides valuable information into the vibrational modes, electronic transitions, and atomic structure of this compound.
The distinct spectral features observed may be attributed to the presence of the nitro group, fluorine atoms, and benzene ring. Additional spectral analysis highlights the influence of these substituents on the overall molecular polarity.
This thorough spectral characterization enhances our appreciation of DFNB and its potential role in various chemical systems.